BONE HEALTH AND GROWTH IN SPINAL MUSCULAR ATROPHY TYPE 2 AND 3

Objective: Spinal muscular atrophy is a lower motor neuron disease, but other parts of the body could be affected. This study compared bone mineral density with metabolism and physical growth rates in patients diagnosed spinal type 2 3. Material Methods: Twenty-six were included (15 for 11 3). Weights heights measured, standard deviation scores determined, body-mass index was calculated. Motor function pubertal assessment performed. Serum calcium, phosphorus, alkaline phosphatase, parathormone, 25-hydroxyvitamin vitamin D levels compared. Spine radiography scoliosis densitometry performed, volumetric calculated age sex. Results: Medians height significantly patients. There no difference between two groups terms serum levels. The ratio higher as its severity, Z-scores same group. Conclusion: showed that mineralization atrophy, mainly 2. Further studies are needed to evaluate health